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PUBLICATIONS
ABVAC40
ABvac40 elicits a predominantly Th2 immune response that supports its excellent safety profile
Poster presentation CTAD 2022—ABVac40 Safety profile information
Montañes M, Martín C, Castillo S et al.
UPDATE PHASE 2 STUDY OF ABVAC40, AN ACTIVE VACCINE ANTI-AΒ40 IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT OR VERY-MILD ALZHEIMER’S DISEASE
Poster Presentation ADPD 2022 – TOP LINE DATA (Part A) Phase 2 ABvac40
Molina E, Castillo S, Lacosta AM et al.
Safety, tolerability and immunogenicity of an active anti-Abeta40 vaccine (ABvac40) in patients with Alzheimer's disease: a randomised, double-blind, placebo-controlled, phase I trial
Lacosta AM, Pascual-Lucas M, Pesini P, et al. Alzheimers Res Ther. 2018; 10:12.
ABtest-ms
Clinical performance of an antibody‑free assay for plasma Aβ42/Aβ40 to detect early alterations of Alzheimer’s disease in individuals with subjective cognitive decline
Pascual-Lucas M, Allué JA, Sarasa L et al.
Alzheimer’s Research & Therapy 2023; 15:2
Detecting amyloid positivity in early Alzheimer’s disease using combinations of plasma Aβ42/Aβ40 and p-tau.
Janelidze S, Palmqvist S, Leuzy A et al.
Alzheimer’s Dement 2022; 18:283-293
Comparative performance of plasma Aβ42/Aβ40 and p‐tau181 for the detection of early brain amyloid deposition in individuals with subjective cognitive decline.
Poster presentation CTAD 2022—ABtest MS FACEHBI Cohort
Pascual-Lucas M, Allué JA, Sarasa L et al.
Plasma Aβ42/Aβ40, measured by a novel mass spectrometric method, identifies early amyloid deposition in individuals at risk of Alzheimer’s disease (FACEHBI Cohort)
Oral Presentation ADPD 2022 – AbtestMS_FACEHBI Allué JA, Sarasa L, Pascual-Lucas M
ACCURATE DISCRIMINATION OF BRAIN AMYLOID STATUS IN THE MULTI-CENTRIC A4 STUDY BY PLASMA Aβ42/Aβ40 MEASURED WITH A NOVEL HPLC-MS/MS METHOD
Poster Presentation ADPD 2022 – AbtestMS_A4 Study
Sarasa L, Pascual-Lucas M, Allué JA et al.
Individualized prognosis of cognitive decline and dementia in mild cognitive impairment based on plasma biomarker combinations
Cullen N, Leuzy A, Palmqvist S et al.
Nature Aging 2021; 1:114–123
The global Alzheimer’s Association round robin study on plasma amyloid β methods
Pannee J, Shaw LM, Korecka M at al.
Alzheimers Dement 2021; 14;13(1):e12242
Head-to-Head Comparison of 8 Plasma Amyloid-β 42/40 Assays in Alzheimer Disease.
Janelidze S, Teunissen CE, Zetterberg H et al.
JAMA Neurol. 2021;78:1375-1382.
Performance of the plasma Aβ42/Aβ40 ratio, measured with a novel HPLC-MS/MS method, as a biomarker of amyloid PET status in a DPUK-KOREAN cohort
Jang H, Kim Js, Lee HJ et al.
Alz Res Therapy 2021; 13:179
ABtest-ia
ABtest-IA: A NEW RELIABLE TOOL FOR THE QUANTIFICATION OF Aβ40 AND Aβ42 IN CSF
Poster presentation AAIC 2022—ABtest IA CSF Validation
Fandos N, Romero J, Pascual-Lucas M et al.
Characterization of pre-analytical sample handling effects on a panel of Alzheimer’s disease–related blood-based biomarkers: Results from the Standardization of Alzheimer’s Blood Biomarkers (SABB) working group.
Verberk IMW, Misdorp E, Koelewijn J et al.
Alzheimers Dement 2022; 18:1484-1497.
The global Alzheimer’s Association round robin study on plasma amyloid β methods
Pannee J, Shaw LM, Korecka M at al.
Alzheimers Dement 2021; 14;13(1):e12242
Longitudinal evaluation of the natural history of amyloid-β in plasma and brain
Burnham SC, Fandos N, Fowler C, et al. Brain Communications. 2020; 2, 1-7.
Total Abeta42/Abeta40 ratio in plasma predicts amyloid-PET status, independent of clinical AD diagnosis
Doecke JD, Pérez-Grijalba V, Fandos N, et al. Neurology. 2020; 94: e1580-e1591.
Plasma Abeta42/40 Ratio Detects Early Stages of Alzheimer's Disease and Correlates with CSF and Neuroimaging Biomarkers in the AB255 Study
Pérez-Grijalba V, Romero J, Pesini P, et al. J Prev Alzheimers Dis. 2019-b; 6:34-41.
Plasma Abeta42/40 ratio alone or combined with FDG-PET can accurately predict amyloid-PET positivity: a cross-sectional analysis from the AB255 Study
Pérez-Grijalba V, Arbizu J, Romero J, et al. Alzheimers Res Ther. 2019; 11:96.
Plasma amyloid beta levels are associated with cerebral amyloid and tau deposition
Risacher SL, Fandos N, Romero J, et al. Alzheimers Dement (Amst). 2019; 11:510-519.
Correlations between plasma and PET beta-amyloid levels in individuals with subjective cognitive decline: the Fundació ACE Healthy Brain Initiative (FACEHBI)
De Rojas I, Romero J, Rodríguez-Gómez O, et al. Alzheimers Res Ther. 2018; 10:119.
Plasma amyloid beta 42/40 ratios as biomarkers for amyloid beta cerebral deposition in cognitively normal individuals.
Fandos N, Pérez-Grijalba V, Pesini P, et al. Alzheimers Dement (Amst). 2017; 8:179-187.
Validation of Immunoassay-Based Tools for the Comprehensive Quantification of Abeta40 and Abeta42 Peptides in Plasma.
Pérez-Grijalba V, Fandos N, Canudas J, et al. J Alzheimers Dis. 2016; 54:751-62.