PUBLICACIONES

Plasma Aβ42/Aβ40, measured by a novel mass spectrometric method, identifies early amyloid deposition in individuals at risk of Alzheimer’s disease (FACEHBI Cohort)

Oral Presentation ADPD 2022 – AbtestMS_FACEHBI

ACCURATE DISCRIMINATION OF BRAIN AMYLOID STATUS IN THE MULTI-CENTRIC A4 STUDY BY PLASMA Aβ42/Aβ40 MEASURED WITH A NOVEL HPLC-MS/MS METHOD

Leticia Sarasa, María Pascual-Lucas, José A. Allué, Sergio Castillo, María Eugenia Sáez, Sara Abdel-Latif, Robert A. Rissman, Jose Terencio and Manuel Sarasa

UPDATE PHASE 2 STUDY OF ABVAC40, AN ACTIVE VACCINE ANTI-AΒ40 IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT OR VERY-MILD ALZHEIMER’S DISEASE

Elisabet Molina, Sergio Castillo, Ana M. Lacosta, Jose A. Allué, Noelia Fandos,Judith Romero, María Montañés,Mª Leticia Sarasa, Jose Terencio, Mercè Boada on behalf of ABvac40 study group and Manuel Sarasa

Longitudinal evaluation of the natural history of amyloid-β in plasma and brain

Burnham SC, Fandos N, Fowler C, et al. Brain Communications. 2020; 2, 1-7.

Total Abeta42/Abeta40 ratio in plasma predicts amyloid-PET status, independent of clinical AD diagnosis

Doecke JD, Pérez-Grijalba V, Fandos N, et al. Neurology. 2020; 94: e1580-e1591.

Plasma Abeta42/40 Ratio Detects Early Stages of Alzheimer's Disease and Correlates with CSF and Neuroimaging Biomarkers in the AB255 Study

Pérez-Grijalba V, Romero J, Pesini P, et al. J Prev Alzheimers Dis. 2019-b; 6:34-41.

Plasma Abeta42/40 ratio alone or combined with FDG-PET can accurately predict amyloid-PET positivity: a cross-sectional analysis from the AB255 Study

Pérez-Grijalba V, Arbizu J, Romero J, et al. Alzheimers Res Ther. 2019; 11:96.

Plasma amyloid beta levels are associated with cerebral amyloid and tau deposition

Risacher SL, Fandos N, Romero J, et al. Alzheimers Dement (Amst). 2019; 11:510-519.

Correlations between plasma and PET beta-amyloid levels in individuals with subjective cognitive decline: the Fundació ACE Healthy Brain Initiative (FACEHBI)

De Rojas I, Romero J, Rodríguez-Gómez O, et al. Alzheimers Res Ther. 2018; 10:119.

Safety, tolerability and immunogenicity of an active anti-Abeta40 vaccine (ABvac40) in patients with Alzheimer's disease: a randomised, double-blind, placebo-controlled, phase I trial

Lacosta AM, Pascual-Lucas M, Pesini P, et al. Alzheimers Res Ther. 2018; 10:12.

Plasma amyloid beta 42/40 ratios as biomarkers for amyloid beta cerebral deposition in cognitively normal individuals.

Fandos N, Pérez-Grijalba V, Pesini P, et al. Alzheimers Dement (Amst). 2017; 8:179-187.

Validation of Immunoassay-Based Tools for the Comprehensive Quantification of Abeta40 and Abeta42 Peptides in Plasma.

Pérez-Grijalba V, Fandos N, Canudas J, et al. J Alzheimers Dis. 2016; 54:751-62.